SCOPE 44 - Introduction of Genetically Modified Organisms into the Environment


Contents

Contributors 
Discussion Participants 
Preface 
Joint SCOPE/COGENE Statement 

SECTION 1 HISTORY OF CONCERNS REGARDING GENETIC MANIPULATION

1 Risk Assessment for Genetic Experimentation and Application 
Anna Marie Skalka
2 Recombinant DNA: Past Lessons and Current Concerns 
Allan Campbell

SECTION 2 GENETIC TRANSFER AND THE ENVIRONMENT 

3 Impact of Human Civilization on Biological Evolution 
Werner Arber
4 Epistatic and Pleiotropic Effects on Genetic Manipulation 
Allan Campbell
5 Modulation of Replication Efficiency by Non-coding Sequences and by the Environment 
Giorgio Bernardi, Regina Goursot, Edda Rayko, René Goursot, Baya Cherif-Zahar, and Roberta Melis
6 Population Consequences of Genetic Design in Sexually Reproducing Organisms
Freddy Bugge Christiansen
7 Evolutionary Consequences of Modifying Cultivated Plants
A. Caplan and M. Van Montagu
8 Organization and Dynamics of the Rhizohium Genome. A Basis for Introducing Novel Arrangements of Genetic Information into the Environment 
Rafael Palacios, Esperanza Martinez, Margarita Flores, David Romero, Susana Brom, Guillermo Dávila, and Daniel Piñero 
9 Engineering Microbes for Function and Safety in the Environment 
D.F. Dwyer and Kenneth N. Timmis
10 Patterns of Establishment and Spread of Animal Viruses
Frank Fenner
11 The Release of Genetically Designed Organisms in the Environment: Lessons from the Study of the Ecology of Biological Invasions 
Harold A. Mooney and James A. Drake

SECTION 3 ASSESSMENT AND REGULATION 

12 The Ecology of Genetically Engineered Organisms: Assessing the Environmental Risks 
Michael J. Crawley
13 Ecological Issues Related to the Release of Genetically Engineered Organisms into the Environment
Simon A. Levin
14 Regulation of Biotechnology: A Perspective on the US 'Coordinated Framework'
David T. Kingsbury
15 Current Trends in the Evaluation of the Impact of Deliberate Release of Microorganisms in the Environment: A Case Study with a Bioinsecticidal Bacterium 
Robert M. Faust and Kunthala Jayaraman
 
The electronic version of this publication has been prepared at
the M S Swaminathan Research Foundation, Chennai, India.